Causes of Insulin Resistance, Symptoms and Treatment Insulin resistance occurs when the body’s cells stop responding well to insulin—a hormone that helps move glucose from the blood into cells for energy. When cells become less responsive to insulin, glucose remains in the bloodstream, causing high blood sugar levels. Over time, this condition can lead to prediabetes, Type 2 Diabetes... https://www.freedomfromdiabetes.org/blog/post/causes-of-insulin-resistance-symptoms-and-treatment/2835