If the choice is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In patients already obtaining an opioid analgesic, prescribe a lower initial dose of the benzodiazepine or other CNS depressant than indicated https://webdirectorytalk.com/listings715490/the-ultimate-guide-to-codeine-huisarts