Pentobarbital will decrease the extent or outcome of clarithromycin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar. pentobarbital will lessen the level or impact of losartan by influencing hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Not known. Use Warning/Monitor. CYP3A4 inducers could increase the metabolism of clopidogrel to its L... https://sodium-pentobarbital73837.loginblogin.com/27929026/the-2-minute-rule-for-sodium-pentobarbital-euthanasia-dose